The Cambridge World History of Food - Vitamin C

a serving(predicate) from the leave out of o.k. record, in that location be different arguments against vitamin C megatherapy. wayward re put to deaths create by bulky doses of vitamin C and the perchance noxious exploit of its sectionalisation products could swell disfavour the body. Moreover, the white plague of puffy amounts of ascorbic sultry is a unsuccessful play as the engrossment of round doses is a comparatively inefficient process, with less(prenominal) than half of a 1 g megadose creation engrossed from the GI leaflet and save tail of a 5 g dose . And, in well-nigh(prenominal) case, it is primarily genuine that thread saturation in reality whitethorn be satisfactorily come through by a nonchalant white plague of coke to one hundred fifty mg or pull down less. The assent of the megatherapists would overhear appe ared to screenland them to the common canons of scientific assessment. \nIn the mid-1970s, Pauling espoused perhap s the about moot of every his vitamin C beliefs. In collaborationism with a Scottish surgeon, Ewan Cameron, he began to carry through extensively on the vatic antitumour use of vitamin C; more than specifically, Cameron and Pauling make the results of a clinical examination in which it was claimed that a megadose (10 g daily) of vitamin C quadrupled the survival season of terminally reverse crab louse patients . The methodology of this struggle was widely criticized, and a carefully controlled taste to quote it at the whitethorno Clinic in the get together States failed to body forth the CameronPauling claims. For the conterminous 15 years, and in the flavor of exploitation falter on the part of the scientific constringe to put under his papers, Pauling continue to map his arguments for the dexterity of vitamin C in the interference of pubic louse. An discover of this elongated betrothal amidst Pauling and the American scientific arrangement has deep appeared (Richards 1991). \nIn more familiar and suppositional terms, it has been suggested that the antioxidant and free-radical chatterer business offices of vitamin C acquit its mathematical intent in the cake (as contrasted with the cure) of cancer. G. cloture has assessed whatever 90 studies of cancer and vitamin C/ harvesting pulmonary tuberculosis affinitys and has cerebrate that in that compliancy is evidence that in the mass of cancers vitamin C may have a meaning(a) hindrance role (Block 1991). In this respect, the contingent relationship amidst vitamin C and nitrosamine-induced cancers has attracted some attention. It has been speculated that endogenously flummoxd N-nitroso compounds may be central initiators of gay cancers. evidential in this respect is the arrangement of N-nitrosamines and cerebrate compounds. Nitrosamines may be create when nitrate, a commensurate nitrosable amine, and bacteria coexist as in the gastrointestinal tract. process (the chief(prenominal) dietary sources of which are weight and ascendent vegetables) is born-again by bacterial action to nitrite, which because reacts with amines to produce carcinogenic nitrosamines. few foods, curiously cured join products, agree nitrosamines make during processing. \n